Based only on the facts in our directory. The right pick still depends on the job you need done.
Lower starting price
Not comparable
Not comparable: CoLumbo does not list a price
Free plan
Tie
Neither has one
Higher rating
CoLumbo
4.2 against 4.1
Same job?
Yes
Both are Healthcare AI tools
Side by side
Compared on
CoLumbo
Ezra AI
Our rating
4.2Better
4.1
Starts at
Not listed
$499/mo
Free plan
No
No
Category
Healthcare AI
Healthcare AI
Plans
See pricing
From $499/mo
Key features
Automated vertebra and disc segmentation on lumbar spine MRI
Pre-populated structured radiology reports
3D video reconstruction of the spine
FDA 510(k), CE mark, and TGA regulatory clearance
Objective, auditable measurements referenced in personal-injury cases
Full-body MRI scanning covering up to 13 organs in a single visit
Ezra Flash AI image enhancement to improve scan clarity
Ezra Assist AI-supported radiologist review, FDA-cleared for prostate imaging
Ezra Reporter plain-English translation of radiology findings for patients
22-minute scan time following integration with Function Health's protocol
Pros
Regulatory clearance across three major markets signals clinical rigor
Cuts radiologist reporting time on a specific, high-volume study type
Structured, auditable output has legal as well as clinical value
AI-assisted imaging pipeline layered on top of licensed radiologist review, not a replacement for one
Scan price dropped substantially after the Function Health acquisition
Founder-driven mission with a decade of scanning volume and multiple US locations
Cons
Pricing is not public and requires direct engagement with the company
Narrow focus on lumbar spine limits use to specific radiology workloads
Requires integration into a facility's existing imaging systems
Now operates as a subsidiary of Function Health rather than an independent company, which may affect long-term product direction
Full-body MRI screening for asymptomatic, average-risk patients remains debated in mainstream clinical guidance
Meaningful ongoing access requires a separate paid Function Health membership, not a one-time fee
Company
Smart-Soft, founded 2021
Ezra, founded 2018
Prices come from each vendor's pricing page, last checked 20260718. Check the vendor before you buy.
FAQ
Questions people ask
Is CoLumbo better than Ezra AI?
In our reviews CoLumbo scores 4.2 and Ezra AI scores 4.1. The better pick depends on the job. CoLumbo: CoLumbo analyzes lumbar spine MRI scans and pre-populates radiology reports with FDA-cleared AI segmentation. Ezra AI: Full-body MRI screening service that uses AI to flag early signs of cancer across up to 13 organs.
CoLumbo
Ezra AI
