Shortlist by what you need
Start here if you know why you are leaving SOPHiA GENETICS.
Want the closest match?
TriomicsMost similar to SOPHiA GENETICS in what it does, its category and its price.
Visit (opens Triomics in a new tab)Need a free plan?
Belong AIHas a free plan, rated 4.2 out of 5. SOPHiA GENETICS has none.
Visit (opens Belong AI in a new tab)Want the best rated?
ArteraRated 4.4 out of 5 in our review, against 3.9 for SOPHiA GENETICS.
Visit (opens Artera in a new tab)
At a glance
Green means better than SOPHiA GENETICS, red means worse. Prices are starting prices per month.
| Tool | Our rating | Starts at | Free plan | Best for | Compare |
|---|---|---|---|---|---|
 SOPHiA GENETICSBaseline | 3.9 | Not listed | No | AI genomic analytics at 98-99% accuracy, deployed across 1,000+ healthcare institutions in 75+ countries - 2.6 million-plus genomic profiles analyzed to date. | |
| Triomics | 4.0+0.1 | Not listed | No | AI for oncology workflows, supporting clinical trial matching and cancer care decisions. | vs SOPHiA GENETICS |
| Artera | 4.4+0.5 | Not listed | No | FDA-cleared multimodal AI that reads biopsy images and clinical data to guide cancer therapy decisions. | vs SOPHiA GENETICS |
 Rayscape | 3.7−0.2 | Not listed | No | FDA-cleared AI that reads chest X-rays and lung CTs for 148+ pathologies, trained on 42M+ medical images - detects, measures, and tracks pulmonary nodules from 3 to 30mm. | vs SOPHiA GENETICS |
 Tempus AI | 4.3+0.4 | Not listed | No | Publicly traded on Nasdaq, guiding to $1.6 billion in 2026 revenue | vs SOPHiA GENETICS |
 Paige | 4.1+0.2 | Not listed | No | Digital pathology AI co-pilot from Memorial Sloan Kettering researchers, acquired by Tempus in 2025 | vs SOPHiA GENETICS |
| Belong AI | 4.2+0.3 | Free | YesSOPHiA GENETICS has none | AI health mentor platform that gives cancer and MS patients conversational support validated by oncologists. | vs SOPHiA GENETICS |
 Enlitic | 3.9Same | Not listed | No | Deep-learning chest X-ray analysis (CXR-AI) sped radiologist interpretation over 20% in early trials - the first U.S. imaging AI company approved to commercialize in Japan. | vs SOPHiA GENETICS |
 Narrativa | 3.6−0.3 | Not listed | No | Agentic AI generates compliant clinical study reports, patient narratives, and regulatory submissions at scale - GxP-ready, GDPR-aligned, and built to an FDA/EMA-aligned safety framework. | vs SOPHiA GENETICS |
The alternatives in detail
In order of how closely each one matches SOPHiA GENETICS.
Triomics
4.0Not listed
vs SOPHiA GENETICS+0.1
AI for oncology workflows, supporting clinical trial matching and cancer care decisions.
- AI built specifically for oncology rather than general medicine
- Clinical trial matching against unstructured patient records
- Structuring of oncology data for downstream decision support
Trial matching addresses a real and higher-priced manual bottleneck
Clinical deployment requires validation and governance review
Artera
4.4Not listed
vs SOPHiA GENETICS+0.5
FDA-cleared multimodal AI that reads biopsy images and clinical data to guide cancer therapy decisions.
- Multimodal AI trained on digitized biopsy images paired with clinical data
- FDA De Novo authorization for the ArteraAI Prostate Test
- FDA clearance for ArteraAI Breast digital pathology risk stratification
Regulatory clearance (FDA De Novo, NCCN guideline inclusion) beyond most AI health startups
Not a self-serve software product; access runs through labs, clinicians, and insurance billing
Rayscape
3.7Not listed
vs SOPHiA GENETICS−0.2
FDA-cleared AI that reads chest X-rays and lung CTs for 148+ pathologies, trained on 42M+ medical images - detects, measures, and tracks pulmonary nodules from 3 to 30mm.
- 148+ pathology detection on chest X-rays
- Pulmonary nodule detection, measurement, and tracking on lung CT
- Multiple FDA clearances and extensive clinical validation
Genuine regulatory clearance (FDA) rather than just a marketing claim
Pricing isn't public - requires direct institutional engagement
Tempus AI
4.3Not listed
vs SOPHiA GENETICS+0.4
Publicly traded on Nasdaq, guiding to $1.6 billion in 2026 revenue.
- Machine learning applied to genomic and clinical data for precision treatment matching
- One of the largest connected libraries of clinical and molecular data
- Publicly traded on Nasdaq under the ticker TEM
Publicly reported financials give unusual transparency into scale and growth
Pricing runs through insurance billing and enterprise agreements, not published rates
Paige
4.1Not listed
vs SOPHiA GENETICS+0.2
Digital pathology AI co-pilot from Memorial Sloan Kettering researchers, acquired by Tempus in 2025.
- Paige Alba AI co-pilot for digital pathology tissue-slide analysis
- Cancer diagnosis, tissue subtyping, and molecular biomarker discovery support
- Founded in 2017 by researchers from Memorial Sloan Kettering Cancer Center
Research pedigree from Memorial Sloan Kettering lends real clinical credibility
Enterprise-only pricing requires a sales conversation before evaluation
Belong AI
4.2Free
vs SOPHiA GENETICS+0.3Free plan
AI health mentor platform that gives cancer and MS patients conversational support validated by oncologists.
- Dave: conversational AI cancer mentor validated by oncologists
- Sophie: AI mentor for multiple sclerosis patients
- Tara: AI clinical-trial matching by medical profile and location
Medical validation from oncologists affiliated with ASCO and ESMO adds real clinical credibility
Exact DavePro subscription pricing is not published on the company site
Enlitic
3.9Not listed
vs SOPHiA GENETICSSame
Deep-learning chest X-ray analysis (CXR-AI) sped radiologist interpretation over 20% in early trials - the first U.S. imaging AI company approved to commercialize in Japan.
- CXR-AI - deep-learning chest X-ray abnormality detection
- ENDEX - AI-based medical image data standardization
- Curie platform for real-world evidence data infrastructure
Regulatory approval (Japan) is a concrete, third-party-verifiable claim
Enterprise healthcare infrastructure - not accessible to individual practitioners or consumers
Narrativa
3.6Not listed
vs SOPHiA GENETICS−0.3
Agentic AI generates compliant clinical study reports, patient narratives, and regulatory submissions at scale - GxP-ready, GDPR-aligned, and built to an FDA/EMA-aligned safety framework.
- Agentic AI generates clinical study reports and patient narratives
- Knowledge graph technology for complex clinical relationships
- GxP-ready validation architecture
Purpose-built compliance architecture (GxP/FDA/EMA-aligned), not generic enterprise AI
No published pricing - an enterprise sales process
FAQ
Questions people ask
Is SOPHiA GENETICS free?
SOPHiA GENETICS does not list a free plan. Check its pricing page for current plans.
What is the best free alternative to SOPHiA GENETICS?
Belong AI is the highest-rated alternative here with a free plan (4.2 out of 5).
How did you pick these alternatives?
We match tools on what they do, their category and their price, using the details in our directory. Ratings come from our reviews and reader reviews.