SOPHiA GENETICS vs Tempus AI (2026): Pricing, Features & Which to Choose

Who comes out ahead

Based only on the facts in our directory. The right pick still depends on the job you need done.

Lower starting price
Not comparable
Not comparable: SOPHiA GENETICS does not list a price
Free plan
Tie
Neither has one
Higher rating
Tempus AI
3.9 against 4.3
Same job?
Yes
Both are Healthcare AI tools

Side by side

Compared on	SOPHiA GENETICS	Tempus AI
Our rating	3.9	4.3Better
Starts at	Not listed	Not listed
Free plan	No	No
Category	Healthcare AI	Healthcare AI
Plans	See pricing	See pricing
Key features	SOPHiA DDM - AI genomic and radiomic analysis platform 98-99% accuracy across 2.6M+ analyzed genomic profiles Oncology coverage - solid tumors, blood cancers, hereditary cancers, liquid biopsy Rare and inherited disorder analysis HIPAA/GDPR-compliant cloud infrastructure	Machine learning applied to genomic and clinical data for precision treatment matching One of the largest connected libraries of clinical and molecular data Publicly traded on Nasdaq under the ticker TEM Q1 2026 revenue of $348.1M, up 36.1% year over year 2026 revenue guidance raised to $1.59-$1.60 billion
Pros	Accuracy claims are backed by scale (2.6M+ profiles), not a small validation sample Deployed across a genuinely large, verifiable institutional network (1,000+ sites, 75+ countries) Covers both oncology and rare/inherited disorder use cases	Publicly reported financials give unusual transparency into scale and growth Massive, growing data library strengthens precision-matching over time Strong, consistent revenue growth across both diagnostics and data segments
Cons	No published pricing - an institutional sales process Built for healthcare institutions, not individual practitioners or patients directly Requires integration into existing clinical genomics/pathology workflows	Pricing runs through insurance billing and enterprise agreements, not published rates Built specifically for precision medicine and oncology, a narrower clinical scope Best suited to institutions already positioned to act on genomic testing results
Company	SOPHiA GENETICS	Tempus AI, founded 2015

Prices come from each vendor's pricing page, last checked 20260824. Check the vendor before you buy.

FAQ

Questions people ask

Is SOPHiA GENETICS better than Tempus AI?

In our reviews SOPHiA GENETICS scores 3.9 and Tempus AI scores 4.3. The better pick depends on the job. SOPHiA GENETICS: AI genomic analytics at 98-99% accuracy, deployed across 1,000+ healthcare institutions in 75+ countries - 2.6 million-plus genomic profiles analyzed to date. Tempus AI: Publicly traded on Nasdaq, guiding to $1.6 billion in 2026 revenue.

Which is cheaper, SOPHiA GENETICS or Tempus AI?

SOPHiA GENETICS: see pricing. Tempus AI: see pricing.

Do SOPHiA GENETICS and Tempus AI have free plans?

Neither lists a free plan.

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